Wordt geladen...

Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η

Somatic hypermutation is programmed base substitutions in the variable regions of Ig genes for high-affinity antibody generation. Two motifs, RGYW and WA (R, purine; Y, pyrimidine; W, A or T), have been found to be somatic hypermutation hotspots. Overwhelming evidence suggests that DNA polymerase η...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Zhao, Ye, Gregory, Mark T., Biertümpfel, Christian, Hua, Yue-Jin, Hanaoka, Fumio, Yang, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657764/
https://ncbi.nlm.nih.gov/pubmed/23630267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303126110
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!