Efficient Syntheses of Vitamin K Chain-Shortened Acid Metabolites

Por Teitelbaum, Aaron M., Scian, Michele, Nelson, Wendel L., Rettie, Allan E.
Publicado no Synthesis (Stuttg) (2015)

Induction of CYP26A1 by Metabolites of Retinoic Acid: Evidence That CYP26A1 Is an Important Enzyme in the Elimination of Active Retinoids

Por Topletz, Ariel R., Tripathy, Sasmita, Foti, Robert S., Shimshoni, Jakob A., Nelson, Wendel L., Isoherranen, Nina
Publicado no Mol Pharmacol (2015)

Identification and Structural Characterization of Three New Metabolites of Bupropion in Humans

Por Sager, Jennifer E., Choiniere, John R., Chang, Justine, Stephenson-Famy, Alyssa, Nelson, Wendel L., Isoherranen, Nina
Publicado no ACS Med Chem Lett (2016)

Comparison of the Function and Expression of CYP26A1 and CYP26B1, the two Retinoic Acid Hydroxylases

Por Topletz, Ariel R., Thatcher, Jayne E., Zelter, Alex, Lutz, Justin D., Tay, Suzanne, Nelson, Wendel L., Isoherranen, Nina
Publicado em 2011

Contribution of Itraconazole Metabolites to Inhibition of CYP3A4 in vivo

Por Templeton, Ian, Thummel, Kenneth E, Kharasch, Evan D, Kunze, Kent L, Hoffer, Christine, Nelson, Wendel L, Isoherranen, Nina
Publicado em 2007

Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and Its Metabolite: Implications for Risk Assessment of Multiple Time-Dependent Inhibitor Systems

Por Lutz, Justin D., VandenBrink, Brooke M., Babu, Katipudi N., Nelson, Wendel L., Kunze, Kent L., Isoherranen, Nina
Publicado em 2013

Sequential Metabolism of Secondary Alkyl Amines to Metabolic-Intermediate Complexes: Opposing Roles for the Secondary Hydroxylamine and Primary Amine Metabolites of Desipramine, (S...

Por Hanson, Kelsey L., VandenBrink, Brooke M., Babu, Kantipudi N., Allen, Kyle E., Nelson, Wendel L., Kunze, Kent L.
Publicado em 2010

Substrate Specificity and Ligand Interactions of CYP26A1, the Human Liver Retinoic Acid Hydroxylase

Por Thatcher, Jayne E., Buttrick, Brian, Shaffer, Scott A., Shimshoni, Jakob A., Goodlett, David R., Nelson, Wendel L., Isoherranen, Nina
Publicado em 2011

Stereospecific Metabolism of Itraconazole by CYP3A4: Dioxolane Ring Scission of Azole Antifungals

Por Peng, Chi-Chi, Shi, Wei, Lutz, Justin D., Kunze, Kent L., Liu, Jun O., Nelson, Wendel L., Isoherranen, Nina
Publicado em 2012

Expression and Functional Characterization of Cytochrome P450 26A1, a Retinoic Acid Hydroxylase

Por Lutz, Justin D, Dixit, Vaishali, Yeung, Catherine K, Dickmann, Leslie J, Zelter, Alex, Thatcher, Jayne E, Nelson, Wendel L, Isoherranen, Nina
Publicado em 2008

Stereoselective Formation and Metabolism of 4-Hydroxy-Retinoic Acid Enantiomers by Cytochrome P450 Enzymes

Por Shimshoni, Jakob A., Roberts, Arthur G., Scian, Michele, Topletz, Ariel R., Blankert, Sean A., Halpert, James R., Nelson, Wendel L., Isoherranen, Nina
Publicado em 2012