The role of metabolites in predicting drug-drug interactions: Focus on irreversible P450 inhibition

Por VandenBrink, Brooke M., Isoherranen, Nina
Publicado em 2010

Stereoselective Inhibition of CYP2C19 and CYP3A4 by Fluoxetine and Its Metabolite: Implications for Risk Assessment of Multiple Time-Dependent Inhibitor Systems

Por Lutz, Justin D., VandenBrink, Brooke M., Babu, Katipudi N., Nelson, Wendel L., Kunze, Kent L., Isoherranen, Nina
Publicado em 2013

Sequential Metabolism of Secondary Alkyl Amines to Metabolic-Intermediate Complexes: Opposing Roles for the Secondary Hydroxylamine and Primary Amine Metabolites of Desipramine, (S...

Por Hanson, Kelsey L., VandenBrink, Brooke M., Babu, Kantipudi N., Allen, Kyle E., Nelson, Wendel L., Kunze, Kent L.
Publicado em 2010