Comparison of the Function and Expression of CYP26A1 and CYP26B1, the two Retinoic Acid Hydroxylases

All-trans-retinoic acid (atRA) is an important signaling molecule in all chordates. The cytochrome P450 enzymes CYP26 are believed to partially regulate cellular concentrations of atRA via oxidative metabolism and hence affect retinoid homeostasis and signaling. CYP26A1 and CYP26B1 are atRA hydroxyl...

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Bibliographic Details
Main Authors: Topletz, Ariel R., Thatcher, Jayne E., Zelter, Alex, Lutz, Justin D., Tay, Suzanne, Nelson, Wendel L., Isoherranen, Nina
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229621/
https://ncbi.nlm.nih.gov/pubmed/22020119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.10.007
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