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The relative importance of CYP26A1 in hepatic clearance of all-trans retinoic acid

All-trans retinoic acid (RA) is a critical signaling molecule and its concentration is tightly regulated. Several P450 enzymes including CYP26A1, CYP2C8, and CYP3A4 have been proposed to be responsible for RA clearance in the liver but their quantitative importance has not been demonstrated. To dete...

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Detalhes bibliográficos
Main Authors: Thatcher, Jayne E., Zelter, Alex, Isoherranen, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906711/
https://ncbi.nlm.nih.gov/pubmed/20513361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.05.023
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