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Biochemical and Physiological Importance of the CYP26 Retinoic Acid Hydroxylases

The Cytochrome P450 (CYP) family 26 enzymes contribute to retinoic acid (RA) metabolism and homeostasis in humans, mammals and other chordates. The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) as well as 9-cisRA and 13-cisR...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Isoherranen, Nina, Zhong, Guo
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881548/
https://ncbi.nlm.nih.gov/pubmed/31419517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2019.107400
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