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Biochemical and Physiological Importance of the CYP26 Retinoic Acid Hydroxylases

The Cytochrome P450 (CYP) family 26 enzymes contribute to retinoic acid (RA) metabolism and homeostasis in humans, mammals and other chordates. The three CYP26 family enzymes, CYP26A1, CYP26B1 and CYP26C1 have all been shown to metabolize all-trans-retinoic acid (atRA) as well as 9-cisRA and 13-cisR...

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Publicado en:Pharmacol Ther
Autores principales: Isoherranen, Nina, Zhong, Guo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881548/
https://ncbi.nlm.nih.gov/pubmed/31419517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2019.107400
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