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Therapeutic Potential of the Inhibition of the Retinoic Acid Hydroxylases CYP26A1 and CYP26B1 by Xenobiotics

Retinoic acid (RA), the active metabolite of vitamin A, is an important endogenous signaling molecule regulating cell cycle and maintenance of epithelia. RA isomers are also used as drugs to treat various cancers and dermatological diseases. However, the therapeutic uses of RA isomers are limited du...

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Bibliografiske detaljer
Udgivet i:Curr Top Med Chem
Main Authors: Nelson, Cara H, Buttrick, Brian R, Isoherranen, Nina
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366427/
https://ncbi.nlm.nih.gov/pubmed/23688132
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