Wordt geladen...
Inhibition of the all-trans Retinoic Acid (atRA) Hydroxylases CYP26A1 and CYP26B1 Results in Dynamic, Tissue-Specific Changes in Endogenous atRA Signaling
All-trans retinoic acid (atRA), the active metabolite of vitamin A, is a ligand for several nuclear receptors and acts as a critical regulator of many physiologic processes. The cytochrome P450 family 26 (CYP26) enzymes are responsible for atRA clearance, and are potential drug targets to increase c...
Bewaard in:
| Gepubliceerd in: | Drug Metab Dispos |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The American Society for Pharmacology and Experimental Therapeutics
2017
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469401/ https://ncbi.nlm.nih.gov/pubmed/28446509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.117.075341 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|