Therapeutic Potential of the Inhibition of the Retinoic Acid Hydroxylases CYP26A1 and CYP26B1 by Xenobiotics

Por Nelson, Cara H, Buttrick, Brian R, Isoherranen, Nina
Publicado no Curr Top Med Chem (2013)

Catalytic vs. Inhibitory Promiscuity in Cytochrome P450s: Implications for Evolution of New Function

Por Foti, Robert S., Honaker, Mathew, Nath, Abhinav, Pearson, Josh T., Buttrick, Brian, Isoherranen, Nina, Atkins, William M.
Publicado em 2011

Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1

Por Foti, Robert S., Isoherranen, Nina, Zelter, Alex, Dickmann, Leslie J., Buttrick, Brian R., Diaz, Philippe, Douguet, Dominique
Publicado no J Pharmacol Exp Ther (2016)

Substrate Specificity and Ligand Interactions of CYP26A1, the Human Liver Retinoic Acid Hydroxylase

Por Thatcher, Jayne E., Buttrick, Brian, Shaffer, Scott A., Shimshoni, Jakob A., Goodlett, David R., Nelson, Wendel L., Isoherranen, Nina
Publicado em 2011

Development and characterization of novel and selective inhibitors of cytochrome P450 CYP26A1, the human liver retinoic acid hydroxylase

Por Diaz, Philippe, Huang, Weize, Keyari, Charles M., Buttrick, Brian, Price, Lauren, Guilloteau, Nicolas, Tripathy, Sasmita, Sperandio, Vanessa G., Fronczek, Frank R., Astruc-Diaz, Fanny, Isoherranen, Nina
Publicado no J Med Chem (2016)