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Identification and Structural Characterization of Three New Metabolites of Bupropion in Humans
[Image: see text] Bupropion is a widely used antidepressant and the recommended CYP2B6 probe drug. However, current understanding of bupropion elimination pathways is limited. Bupropion has three active circulating metabolites, OH-bupropion, threohydrobupropion, and erythrohydrobupropion, but togeth...
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| Pubblicato in: | ACS Med Chem Lett |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2016
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026406/ https://ncbi.nlm.nih.gov/pubmed/27660681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00189 |
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