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Identification of non‐reported bupropion metabolites in human plasma

Bupropion and its three active metabolites exhibit clinical efficacy in the treatment of major depression, seasonal depression and smoking cessation. The pharmacokinetics of bupropion in humans is highly variable. It is not known if there are any non‐reported metabolites formed in humans in addition...

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Detalhes bibliográficos
Publicado no:Biopharm Drug Dispos
Main Authors: Connarn, Jamie N., Luo, Ruijuan, Windak, Jim, Zhang, Xinyuan, Babiskin, Andrew, Kelly, Marisa, Harrington, Gloria, Ellingrod, Vicki L., Kamali, Masoud, McInnis, Melvin, Sun, Duxin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132048/
https://ncbi.nlm.nih.gov/pubmed/27723114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.2046
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