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Metabolism of Bupropion by Carbonyl Reductases in Liver and Intestine
Bupropion’s metabolism and the formation of hydroxybupropion in the liver by cytochrome P450 2B6 (CYP2B6) has been extensively studied; however, the metabolism and formation of erythro/threohydrobupropion in the liver and intestine by carbonyl reductases (CR) has not been well characterized. The pur...
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| Publicado no: | Drug Metab Dispos |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6067387/ https://ncbi.nlm.nih.gov/pubmed/25904761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.063107 |
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