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Pharmacogenetics of Human Carbonyl Reductase 1 (CBR1) in Livers from Black and White Donors
Carbonyl reductase 1 (CBR1) reduces the anticancer drug doxorubicin into the cardiotoxic metabolite doxorubicinol. We documented the hepatic expression of CBR1 in samples from white and black donors. Concordance between ethnicity and geographical ancestry was examined with ancestry informative marke...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680526/ https://ncbi.nlm.nih.gov/pubmed/19022938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.024547 |
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