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Identification of non‐reported bupropion metabolites in human plasma

Bupropion and its three active metabolites exhibit clinical efficacy in the treatment of major depression, seasonal depression and smoking cessation. The pharmacokinetics of bupropion in humans is highly variable. It is not known if there are any non‐reported metabolites formed in humans in addition...

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Bibliografiska uppgifter
I publikationen:Biopharm Drug Dispos
Huvudupphovsmän: Connarn, Jamie N., Luo, Ruijuan, Windak, Jim, Zhang, Xinyuan, Babiskin, Andrew, Kelly, Marisa, Harrington, Gloria, Ellingrod, Vicki L., Kamali, Masoud, McInnis, Melvin, Sun, Duxin
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132048/
https://ncbi.nlm.nih.gov/pubmed/27723114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.2046
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