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Interaction between COMT rs5993883 and second generation antipsychotics is linked to decreases in verbal cognition and cognitive control in bipolar disorder

BACKGROUND: Second generation antipsychotics (SGAs) are increasingly utilized in Bipolar Disorder (BD) but are potentially associated with cognitive side effects. Also linked to cognitive deficits associated with SGA-treatment are catechol-O-methyltransferase (COMT) gene variants. In this study, we...

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Detalhes bibliográficos
Publicado no:BMC Psychol
Main Authors: Flowers, Stephanie A., Ryan, Kelly A., Lai, Zongshan, McInnis, Melvin G., Ellingrod, Vicki L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818866/
https://ncbi.nlm.nih.gov/pubmed/27039372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40359-016-0118-3
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