Terminal Deoxynucleotidyl Transferase: The Story of a Misguided DNA Polymerase

Por Motea, Edward A., Berdis, Anthony J.
Publicado em 2009

Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis

Por Motea, Edward A., Lee, Irene, Berdis, Anthony J.
Publicado em 2011

Development of a ‘clickable’ non-natural nucleotide to visualize the replication of non-instructional DNA lesions

Por Motea, Edward A., Lee, Irene, Berdis, Anthony J.
Publicado em 2012

A Non-Natural Nucleoside with Combined Therapeutic and Diagnostic Activities Against Leukemia

Por Motea, Edward A., Lee, Irene, Berdis, Anthony J.
Publicado em 2012

The Mechanism and Dynamics of Translesion DNA Synthesis Catalyzed by the Escherichia coli Klenow fragment

Por Sheriff, Asim, Motea, Edward, Lee, Irene, Berdis, Anthony J.
Publicado em 2008

Replication of a Universal Nucleobase Provides Unique Insight into the Role of Entropy During DNA Polymerization and Pyrophosphorolysis

Por Zhang, Xuemei, Motea, Edward, Lee, Irene, Berdis, Anthony J.
Publicado em 2010

Inhibiting translesion DNA synthesis as an approach to combat drug resistance to DNA damaging agents

Por Choi, Jung-Suk, Kim, Seol, Motea, Edward, Berdis, Anthony
Publicado no Oncotarget (2017)

Evaluating the Therapeutic Potential of a Non-Natural Nucleotide that Inhibits Human Ribonucleotide Reductase

Por Ahmad, Faiz, Wan, Qun, Jha, Shalini, Motea, Edward, Berdis, Anthony, Dealwis, Chris
Publicado em 2012

XRN2 Links Transcription Termination to DNA Damage and Replication Stress

Por Morales, Julio C., Richard, Patricia, Patidar, Praveen L., Motea, Edward A., Dang, Tuyen T., Manley, James L., Boothman, David A.
Publicado no PLoS Genet (2016)

The Kub5-Hera/RPRD1B interactome: a novel role in preserving genetic stability by regulating DNA mismatch repair

Por Patidar, Praveen L., Motea, Edward A., Fattah, Farjana J., Zhou, Yunyun, Morales, Julio C., Xie, Yang, Garner, Harold R., Boothman, David A.
Publicado no Nucleic Acids Res (2016)

Modulators of Redox Metabolism in Head and Neck Cancer

Por Chen, Xiaofei, Mims, Jade, Huang, Xiumei, Singh, Naveen, Motea, Edward, Planchon, Sarah M., Beg, Muhammad, Tsang, Allen W., Porosnicu, Mercedes, Kemp, Melissa L., Boothman, David A., Furdui, Cristina M.
Publicado no Antioxid Redox Signal (2018)

Kub5-Hera(RPRD1B) deficiency promotes “BRCAness” and vulnerability to PARP inhibition in BRCA-proficient Breast Cancers

Por Motea, Edward A., Fattah, Farjana J., Xiao, Ling, Girard, Luc, Rommel, Amy, Morales, Julio C., Patidar, Praveen L., Zhou, Yunyun, Porter, Andrew C., Xie, Yang, Minna, John D., Boothman, David A.
Publicado no Clin Cancer Res (2018)

Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair

Por Morales, Julio C., Richard, Patricia, Rommel, Amy, Fattah, Farjana J., Motea, Edward A., Patidar, Praveen L., Xiao, Ling, Leskov, Konstantin, Wu, Shwu-Yuan, Hittelman, Walter N., Chiang, Cheng-Ming, Manley, James L., Boothman, David A.
Publicado em 2014

Tumor-Selective, Futile Redox Cycle-Induced Bystander Effects Elicited by NQO1 Bioactivatable Radiosensitizing Drugs in Triple-Negative Breast Cancers

Por Cao, Lifen, Li, Long Shan, Spruell, Christopher, Xiao, Ling, Chakrabarti, Gaurab, Bey, Erik A., Reinicke, Kathryn E., Srougi, Melissa C., Moore, Zachary, Dong, Ying, Vo, Peggy, Kabbani, Wareef, Yang, Chin-Rang, Wang, Xiaoyu, Fattah, Farjana, Morales, Julio C., Motea, Edward A., Bornmann, William G., Yordy, John S., Boothman, David A.
Publicado em 2014

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase (PARP) Inhibitors

Por Huang, Xiumei, Motea, Edward A., Moore, Zachary R., Yao, Jun, Dong, Ying, Chakrabarti, Gaurab, Kilgore, Jessica A., Silvers, Molly A., Patidar, Praveen L., Cholka, Agnieszka, Fattah, Farjana, Cha, Yoonjeong, Anderson, Glenda G., Kusko, Rebecca, Peyton, Michael, Yan, Jingsheng, Xie, Xian-Jin, Sarode, Venetia, Williams, Noelle S., Minna, John D., Beg, Muhammad, Gerber, David E., Bey, Erik A., Boothman, David A.
Publicado no Cancer Cell (2016)