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The Mechanism and Dynamics of Translesion DNA Synthesis Catalyzed by the Escherichia coli Klenow fragment

Translesion DNA synthesis represents the ability of a DNA polymerase to incorporate and extend beyond damaged DNA. In this report, the mechanism and dynamics by which the Escherichia coli Klenow fragment performs translesion DNA synthesis during the misreplication of an abasic site were investigated...

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Detalhes bibliográficos
Main Authors: Sheriff, Asim, Motea, Edward, Lee, Irene, Berdis, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692461/
https://ncbi.nlm.nih.gov/pubmed/18652487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800324r
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