Translesional synthesis on a DNA template containing N(2)-methyl-2′-deoxyguanosine catalyzed by the Klenow fragment of Escherichia coli DNA polymerase I

Formaldehyde is produced in most living systems and is present in the environment. Evidence that formaldehyde causes cancer in experimental animals infers that it may be a carcinogenic hazard to humans. Formaldehyde reacts with the exocyclic amino group of deoxyguanosine, resulting in the formation...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Yasui, Manabu, Matsui, Saburo, Ihara, Masaru, Laxmi, Y. R. Santosh, Shibutani, Shinya, Matsuda, Tomonari
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC37255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11328885/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.9.1994
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