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Translesional synthesis on a DNA template containing N(2)-methyl-2′-deoxyguanosine catalyzed by the Klenow fragment of Escherichia coli DNA polymerase I

Formaldehyde is produced in most living systems and is present in the environment. Evidence that formaldehyde causes cancer in experimental animals infers that it may be a carcinogenic hazard to humans. Formaldehyde reacts with the exocyclic amino group of deoxyguanosine, resulting in the formation...

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Detalhes bibliográficos
Main Authors: Yasui, Manabu, Matsui, Saburo, Ihara, Masaru, Laxmi, Y. R. Santosh, Shibutani, Shinya, Matsuda, Tomonari
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC37255/
https://ncbi.nlm.nih.gov/pubmed/11328885
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