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A Non-Natural Nucleoside with Combined Therapeutic and Diagnostic Activities Against Leukemia

Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer, presenting with approximately 5,000 new cases each year in the United States. An interesting enzyme implicated in this disease is terminal deoxynucleotidyl transferase (TdT), a specialized DNA polymerase involved in V(D)...

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Detalhes bibliográficos
Main Authors: Motea, Edward A., Lee, Irene, Berdis, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376215/
https://ncbi.nlm.nih.gov/pubmed/22390204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300038f
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