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Non-Natural Nucleotides as Probes for the Mechanism and Fidelity of DNA Polymerases

DNA is a remarkable macromolecule that functions primarily as the carrier of the genetic information of organisms ranging from viruses to bacteria to eukaryotes. The ability of DNA polymerases to efficiently and accurately replicate genetic material represents one of the most fundamental yet complex...

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Autors principals: Lee, Irene, Berdis, Anthony J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149816/
https://ncbi.nlm.nih.gov/pubmed/19733263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.08.023
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