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DNA Polymerases as Therapeutic Targets

Numerous pathological states including cancer, autoimmune diseases, and viral/bacterial infections are often attributed to uncontrollable DNA replication. Inhibiting this essential biological process provides an obvious therapeutic target against these diseases. A logical target is the DNA polymeras...

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Bibliographic Details
Main Author: Berdis, Anthony J.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692436/
https://ncbi.nlm.nih.gov/pubmed/18642851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801179f
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