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Nucleotide Analogues as Probes for DNA and RNA Polymerases

Nucleotide analogues represent a major class of anti-cancer and anti-viral drugs, and provide an extremely powerful tool for dissecting the mechanisms of DNA and RNA polymerases. While the basic assays themselves are relatively straight-forward, a key issue is to appropriately design the studies to...

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Autor principal: Kuchta, Robert D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149870/
https://ncbi.nlm.nih.gov/pubmed/21822500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch090203
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