Učitavanje...
Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues
DNA polymerases select for the incorporation of deoxyribonucleotide triphosphates (dNTPs) using amino acid side-chains that act as a “steric-gate” to bar improper incorporation of rNTPs. An additional factor in the selection of nucleotide substrates resides in the preferred geometry for the furanose...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3563936/ https://ncbi.nlm.nih.gov/pubmed/23050956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301043k |
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