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A nucleotide analogue induced gain of function corrects the error-prone nature of human DNA polymerase iota
Y-family DNA polymerases participate in replication stress and DNA damage tolerance mechanisms. The properties that allow these enzymes to copy past bulky adducts or distorted template DNA can result in a greater propensity for them to make mistakes. Of the four human Y-family members, human DNA pol...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392044/ https://ncbi.nlm.nih.gov/pubmed/22632140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja304176q |
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