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Incorporation of the fluorescent ribonucleotide analogue tCTP by T7 RNA polymerase

Fluorescent RNA is an important analytical tool in medical diagnostics, RNA cytochemistry and RNA aptamer development. We have synthesized the fluorescent ribonucleotide analogue 1,3-diaza-2-oxophenothiazine-ribose-5′-triphosphate (tCTP) and tested it as substrate for T7 RNA polymerase in transcript...

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Detalhes bibliográficos
Main Authors: Stengel, Gudrun, Urban, Milan, Purse, Byron W., Kuchta, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819109/
https://ncbi.nlm.nih.gov/pubmed/20067253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac902456n
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