Synthesis and RNA polymerase incorporation of the degenerate ribonucleotide analogue rPTP.

The synthesis and enzymatic incorporation into RNA of the hydrogen bond degenerate nucleoside analogue 6-(beta-d-ribofuranosyl)-3, 4-dihydro-8H-pyrimido[4,5-c]-[1,2]oxazin-7-one (P) is described. The 5'-triphosphate of this analogue is readily incorporated by T3, T7 and SP6 RNA polymerases into...

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Bibliografische gegevens
Hoofdauteurs: Moriyama, K, Negishi, K, Briggs, M S, Smith, C L, Hill, F, Churcher, M J, Brown, D M, Loakes, D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147510/
https://ncbi.nlm.nih.gov/pubmed/9547267
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