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Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired
Incorporation of ribonucleotides into DNA during genome replication is a significant source of genomic instability. The frequency of ribonucleotides in DNA is determined by deoxyribonucleoside triphosphate/ribonucleoside triphosphate (dNTP/rNTP) ratios, by the ability of DNA polymerases to discrimin...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5703314/ https://ncbi.nlm.nih.gov/pubmed/29109257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713085114 |
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