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Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA

Previous work has demonstrated the presence of ribonucleotides in human mitochondrial DNA (mtDNA) and in the present study we use a genome-wide approach to precisely map the location of these. We find that ribonucleotides are distributed evenly between the heavy- and light-strand of mtDNA. The relat...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Berglund, Anna-Karin, Navarrete, Clara, Engqvist, Martin K. M., Hoberg, Emily, Szilagyi, Zsolt, Taylor, Robert W., Gustafsson, Claes M., Falkenberg, Maria, Clausen, Anders R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336301/
https://ncbi.nlm.nih.gov/pubmed/28207748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006628
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