Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

Ribonucleotides are frequently incorporated into DNA during eukaryotic replication. Here we map the genome-wide distribution of these ribonucleotides as markers of replication enzymology in budding yeast, using a new 5′-DNA end-mapping method, Hydrolytic End Sequencing. HydEn-Seq of DNA from ribonuc...

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Библиографические подробности
Опубликовано в: :Nat Struct Mol Biol
Главные авторы: Clausen, Anders R., Lujan, Scott A., Burkholder, Adam B., Orebaugh, Clinton D., Williams, Jessica S., Clausen, Maryam F., Malc, Ewa P., Mieczkowski, Piotr A., Fargo, David C., Smith, Duncan J., Kunkel, Thomas A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351163/
https://ncbi.nlm.nih.gov/pubmed/25622295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2957
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