Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

Ribonucleotides are frequently incorporated into DNA during eukaryotic replication. Here we map the genome-wide distribution of these ribonucleotides as markers of replication enzymology in budding yeast, using a new 5′-DNA end-mapping method, Hydrolytic End Sequencing. HydEn-Seq of DNA from ribonuc...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Struct Mol Biol
Hlavní autoři: Clausen, Anders R., Lujan, Scott A., Burkholder, Adam B., Orebaugh, Clinton D., Williams, Jessica S., Clausen, Maryam F., Malc, Ewa P., Mieczkowski, Piotr A., Fargo, David C., Smith, Duncan J., Kunkel, Thomas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351163/
https://ncbi.nlm.nih.gov/pubmed/25622295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2957
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky