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Evidence that ribonucleotides are signals for mismatch repair of leading strand replication errors
To maintain genome stability, mismatch repair of nuclear DNA replication errors must be directed to the nascent strand, likely by DNA ends and PCNA. Here we show that the efficiency of mismatch repair in Saccharomyces cerevisiae is reduced by inactivating RNase H2, which nicks DNA containing ribonuc...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658170/ https://ncbi.nlm.nih.gov/pubmed/23603118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.017 |
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