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Topoisomerase 1-mediated Removal of Ribonucleotides from Nascent Leading Strand DNA

RNase H2-dependent Ribonucleotide Excision Repair (RER) removes ribonucleotides incorporated during DNA replication. When RER is defective, ribonucleotides in the nascent leading strand of the yeast genome are associated with replication stress and genome instability. Here we provide evidence that t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Williams, Jessica S., Smith, Dana J., Marjavaara, Lisette, Lujan, Scott A., Chabes, Andrei, Kunkel, Thomas A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595360/
https://ncbi.nlm.nih.gov/pubmed/23375499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.021
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