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Topoisomerase 1-mediated Removal of Ribonucleotides from Nascent Leading Strand DNA

RNase H2-dependent Ribonucleotide Excision Repair (RER) removes ribonucleotides incorporated during DNA replication. When RER is defective, ribonucleotides in the nascent leading strand of the yeast genome are associated with replication stress and genome instability. Here we provide evidence that t...

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Bibliografski detalji
Glavni autori: Williams, Jessica S., Smith, Dana J., Marjavaara, Lisette, Lujan, Scott A., Chabes, Andrei, Kunkel, Thomas A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595360/
https://ncbi.nlm.nih.gov/pubmed/23375499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.021
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