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Topoisomerase 1-mediated Removal of Ribonucleotides from Nascent Leading Strand DNA
RNase H2-dependent Ribonucleotide Excision Repair (RER) removes ribonucleotides incorporated during DNA replication. When RER is defective, ribonucleotides in the nascent leading strand of the yeast genome are associated with replication stress and genome instability. Here we provide evidence that t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595360/ https://ncbi.nlm.nih.gov/pubmed/23375499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.021 |
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