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Topoisomerase 1-mediated Removal of Ribonucleotides from Nascent Leading Strand DNA

RNase H2-dependent Ribonucleotide Excision Repair (RER) removes ribonucleotides incorporated during DNA replication. When RER is defective, ribonucleotides in the nascent leading strand of the yeast genome are associated with replication stress and genome instability. Here we provide evidence that t...

詳細記述

保存先:
書誌詳細
主要な著者: Williams, Jessica S., Smith, Dana J., Marjavaara, Lisette, Lujan, Scott A., Chabes, Andrei, Kunkel, Thomas A.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595360/
https://ncbi.nlm.nih.gov/pubmed/23375499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.021
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