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Topoisomerase 1-mediated Removal of Ribonucleotides from Nascent Leading Strand DNA
RNase H2-dependent Ribonucleotide Excision Repair (RER) removes ribonucleotides incorporated during DNA replication. When RER is defective, ribonucleotides in the nascent leading strand of the yeast genome are associated with replication stress and genome instability. Here we provide evidence that t...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595360/ https://ncbi.nlm.nih.gov/pubmed/23375499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.12.021 |
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