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Evidence that ribonucleotides are signals for mismatch repair of leading strand replication errors
To maintain genome stability, mismatch repair of nuclear DNA replication errors must be directed to the nascent strand, likely by DNA ends and PCNA. Here we show that the efficiency of mismatch repair in Saccharomyces cerevisiae is reduced by inactivating RNase H2, which nicks DNA containing ribonuc...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3658170/ https://ncbi.nlm.nih.gov/pubmed/23603118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.017 |
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