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Development of a ‘clickable’ non-natural nucleotide to visualize the replication of non-instructional DNA lesions
The misreplication of damaged DNA is an important biological process that produces numerous adverse effects on human health. This report describes the synthesis and characterization of a non-natural nucleotide, designated 3-ethynyl-5-nitroindolyl-2′-deoxyriboside triphosphate (3-Eth-5-NITP), as a no...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300027/ https://ncbi.nlm.nih.gov/pubmed/22086959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr980 |
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