Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice

Por Garcia-Miralles, Marta, Geva, Michal, Tan, Jing Ying, Yusof, Nur Amirah Binte Mohammad, Cha, Yoonjeong, Kusko, Rebecca, Tan, Liang Juin, Xu, Xiaohong, Grossman, Iris, Orbach, Aric, Hayden, Michael R., Pouladi, Mahmoud A.
Publicado no JCI Insight (2017)

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

Por Kusko, Rebecca, Dreymann, Jennifer, Ross, Jermaine, Cha, Yoonjeong, Escalante-Chong, Renan, Garcia-Miralles, Marta, Tan, Liang Juin, Burczynski, Michael E., Zeskind, Ben, Laifenfeld, Daphna, Pouladi, Mahmoud, Geva, Michal, Grossman, Iris, Hayden, Michael R.
Publicado no Mol Neurodegener (2018)

Pridopidine activates neuroprotective pathways impaired in Huntington Disease

Por Geva, Michal, Kusko, Rebecca, Soares, Holly, Fowler, Kevin D., Birnberg, Tal, Barash, Steve, -Wagner, Avia Merenlender, Fine, Tania, Lysaght, Andrew, Weiner, Brian, Cha, Yoonjeong, Kolitz, Sarah, Towfic, Fadi, Orbach, Aric, Laufer, Ralph, Zeskind, Ben, Grossman, Iris, Hayden, Michael R.
Publicado no Hum Mol Genet (2016)

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase (PARP) Inhibitors

Por Huang, Xiumei, Motea, Edward A., Moore, Zachary R., Yao, Jun, Dong, Ying, Chakrabarti, Gaurab, Kilgore, Jessica A., Silvers, Molly A., Patidar, Praveen L., Cholka, Agnieszka, Fattah, Farjana, Cha, Yoonjeong, Anderson, Glenda G., Kusko, Rebecca, Peyton, Michael, Yan, Jingsheng, Xie, Xian-Jin, Sarode, Venetia, Williams, Noelle S., Minna, John D., Beg, Muhammad, Gerber, David E., Bey, Erik A., Boothman, David A.
Publicado no Cancer Cell (2016)