Multiple sclerosis pharmacogenetics: personalized approach towards tailored therapeutics

Por Grossman, Iris, Miller, Ariel
Publicado em 2010

Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma

Por Grossman, Iris, Ilani, Tal, Fleishman, Sarel Jacob, Fass, Deborah
Publicado no Protein Eng Des Sel (2016)

Biobanking in Israel 2016–17; expressed perceptions versus real life enrollment

Por Koren, Gideon, Beller, Daniella, Laifenfeld, Daphna, Grossman, Iris, Shalev, Varda
Publicado no BMC Med Ethics (2017)

Trick or treat: The effect of placebo on the power of pharmacogenetic association studies

Por Singer, Clara, Grossman, Iris, Avidan, Nili, Beckmann, Jacques S, Pe'er, Itsik
Publicado em 2005

Enzyme structure captures four cysteines aligned for disulfide relay

Por Gat, Yair, Vardi-Kilshtain, Alexandra, Grossman, Iris, Major, Dan Thomas, Fass, Deborah
Publicado em 2014

The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease

Por Ryskamp, Daniel, Wu, Jun, Geva, Michal, Kusko, Rebecca, Grossman, Iris, Hayden, Michael, Bezprozvanny, Ilya
Publicado no Neurobiol Dis (2016)

Single-molecule spectroscopy exposes hidden states in an enzymatic electron relay

Por Grossman, Iris, Yuval Aviram, Haim, Armony, Gad, Horovitz, Amnon, Hofmann, Hagen, Haran, Gilad, Fass, Deborah
Publicado no Nat Commun (2015)

Alzheimer’s disease: diagnostics, prognostics and the road to prevention

Por Grossman, Iris, Lutz, Michael W., Crenshaw, Donna G., Saunders, Ann M., Burns, Daniel K., Roses, Allen D.
Publicado em 2010

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis

Por Need, Anna C, Keefe, Richard SE, Ge, Dongliang, Grossman, Iris, Dickson, Sam, McEvoy, Joseph P, Goldstein, David B
Publicado em 2009

The Dynamic Disulfide Relay of Quiescin Sulfhydryl Oxidase

Por Alon, Assaf, Grossman, Iris, Gat, Yair, Kodali, Vamsi K., DiMaio, Frank, Mehlman, Tevie, Haran, Gilad, Baker, David, Thorpe, Colin, Fass, Deborah
Publicado em 2012

Characterizing patient compliance over six months in remote digital trials of Parkinson’s and Huntington disease

Por Cohen, Shani, Waks, Zeev, Elm, Jordan J., Gordon, Mark Forrest, Grachev, Igor D., Navon-Perry, Leehee, Fine, Shai, Grossman, Iris, Papapetropoulos, Spyros, Savola, Juha-Matti
Publicado no BMC Med Inform Decis Mak (2018)

A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis

Por Ross, Colin J., Towfic, Fadi, Shankar, Jyoti, Laifenfeld, Daphna, Thoma, Mathis, Davis, Matthew, Weiner, Brian, Kusko, Rebecca, Zeskind, Ben, Knappertz, Volker, Grossman, Iris, Hayden, Michael R.
Publicado no Genome Med (2017)

Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs).

Por Matchar, David B, Thakur, Mugdha E, Grossman, Iris, McCrory, Douglas C, Orlando, Lori A, Steffens, David C, Goldstein, David B, Cline, Kathryn E, Gray, Rebecca N
Publicado no Evid Rep Technol Assess (Full Rep) (2007)

Genetic Determinants of Variable Metabolism Have Little Impact on the Clinical Use of Leading Antipsychotics in the CATIE study

Por Grossman, Iris, Sullivan, Patrick F., Walley, Nicole, Liu, Youfang, Dawson, Jeffrey R., Gumbs, Curtis, Gaedigk, Andrea, Leeder, J. Steven, McEvoy, Joseph P., Weale, Michael E., Goldstein, David B.
Publicado em 2008

Using genetics to enable Alzheimer’s disease prevention studies

Por Crenshaw, Donna G, Gottschalk, William K, Lutz, Michael W, Grossman, Iris, Saunders, Ann M, Burke, James R., Welsh-Bohmer, Kathleen A., Brannan, Stephen K., Burns, Daniel K, Roses, Allen D
Publicado em 2012

Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice

Por Garcia-Miralles, Marta, Geva, Michal, Tan, Jing Ying, Yusof, Nur Amirah Binte Mohammad, Cha, Yoonjeong, Kusko, Rebecca, Tan, Liang Juin, Xu, Xiaohong, Grossman, Iris, Orbach, Aric, Hayden, Michael R., Pouladi, Mahmoud A.
Publicado no JCI Insight (2017)

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

Por Kusko, Rebecca, Dreymann, Jennifer, Ross, Jermaine, Cha, Yoonjeong, Escalante-Chong, Renan, Garcia-Miralles, Marta, Tan, Liang Juin, Burczynski, Michael E., Zeskind, Ben, Laifenfeld, Daphna, Pouladi, Mahmoud, Geva, Michal, Grossman, Iris, Hayden, Michael R.
Publicado no Mol Neurodegener (2018)

Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

Por Kolitz, Sarah, Hasson, Tal, Towfic, Fadi, Funt, Jason M., Bakshi, Shlomo, Fowler, Kevin D., Laifenfeld, Daphna, Grinspan, Augusto, Artyomov, Maxim N., Birnberg, Tal, Schwartz, Rivka, Komlosh, Arthur, Hayardeny, Liat, Ladkani, David, Hayden, Michael R., Zeskind, Benjamin, Grossman, Iris
Publicado no Sci Rep (2015)

Response to the Letter-to-the Editor by Cohen et al. concerning our eNeurologicalSci article, Melamed-Gal, et al. Physicochemical, biological, functional and toxicological characte...

Por Melamed-Gal, Sigal, Loupe, Pippa, Timan, Bracha, Weinstein, Vera, Kolitz, Sarah, Zhang, Jenny, Funt, Jason, Komlosh, Arthur, Ashkenazi, Nurit, Bar-Ilan, Oren, Konya, Attila, Beriozkin, Olga, Laifenfeld, Daphna, Hasson, Tal, Zeskind, Benjamin, Hayden, Michael, Nock, Steffen, Grossman, Iris
Publicado no eNeurologicalSci (2018)

Pridopidine activates neuroprotective pathways impaired in Huntington Disease

Por Geva, Michal, Kusko, Rebecca, Soares, Holly, Fowler, Kevin D., Birnberg, Tal, Barash, Steve, -Wagner, Avia Merenlender, Fine, Tania, Lysaght, Andrew, Weiner, Brian, Cha, Yoonjeong, Kolitz, Sarah, Towfic, Fadi, Orbach, Aric, Laufer, Ralph, Zeskind, Ben, Grossman, Iris, Hayden, Michael R.
Publicado no Hum Mol Genet (2016)