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Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

Glatiramer Acetate (GA) has provided safe and effective treatment for multiple sclerosis (MS) patients for two decades. It acts as an antigen, yet the precise mechanism of action remains to be fully elucidated, and no validated pharmacokinetic or pharmacodynamic biomarkers exist. In order to better...

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Publicat a:Sci Rep
Autors principals: Kolitz, Sarah, Hasson, Tal, Towfic, Fadi, Funt, Jason M., Bakshi, Shlomo, Fowler, Kevin D., Laifenfeld, Daphna, Grinspan, Augusto, Artyomov, Maxim N., Birnberg, Tal, Schwartz, Rivka, Komlosh, Arthur, Hayardeny, Liat, Ladkani, David, Hayden, Michael R., Zeskind, Benjamin, Grossman, Iris
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441120/
https://ncbi.nlm.nih.gov/pubmed/25998228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10191
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