Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

Glatiramer Acetate (GA) has provided safe and effective treatment for multiple sclerosis (MS) patients for two decades. It acts as an antigen, yet the precise mechanism of action remains to be fully elucidated, and no validated pharmacokinetic or pharmacodynamic biomarkers exist. In order to better...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kolitz, Sarah, Hasson, Tal, Towfic, Fadi, Funt, Jason M., Bakshi, Shlomo, Fowler, Kevin D., Laifenfeld, Daphna, Grinspan, Augusto, Artyomov, Maxim N., Birnberg, Tal, Schwartz, Rivka, Komlosh, Arthur, Hayardeny, Liat, Ladkani, David, Hayden, Michael R., Zeskind, Benjamin, Grossman, Iris
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441120/
https://ncbi.nlm.nih.gov/pubmed/25998228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10191
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