Genetic Heterogeneity in the rRNA Gene Locus of Trichophyton tonsurans

Por Gaedigk, Andrea, Gaedigk, Roger, Abdel-Rahman, Susan M.
Publicado em 2003

Multilocus Genotyping Identifies Infections by Multiple Strains of Trichophyton tonsurans

Por Abdel-Rahman, Susan M., Preuett, Barry, Gaedigk, Andrea
Publicado em 2007

Impact of the CYP2C19*17 Allele on the Pharmacokinetics of Omeprazole and Pantoprazole in Children: Evidence for a Differential Effect

Por Kearns, Gregory L., Steven Leeder, J., Gaedigk, Andrea
Publicado em 2010

CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification: Resolution of a Complex Genotype and a Discordant Genotype Involving the CYP2D6*59 Allele

Por Gaedigk, Andrea, Riffel, Amanda K., Leeder, J. Steven
Publicado no J Mol Diagn (2015)

High-resolution melt analysis to detect sequence variations in highly homologous gene regions: application to CYP2B6

Por Twist, Greyson P, Gaedigk, Roger, Leeder, J Steven, Gaedigk, Andrea
Publicado em 2013

Prediction of CYP2D6 phenotype from genotype across world populations

Por Gaedigk, Andrea, Sangkuhl, Katrin, Whirl-Carrillo, Michelle, Klein, Teri, Leeder, J. Steven
Publicado no Genet Med (2017)

Maribavir Pharmacokinetics and the Effects of Multiple-Dose Maribavir on Cytochrome P450 (CYP) 1A2, CYP 2C9, CYP 2C19, CYP 2D6, CYP 3A, N-Acetyltransferase-2, and Xanthine Oxidase...

Por Ma, Joseph D., Nafziger, Anne N., Villano, Stephen A., Gaedigk, Andrea, Bertino, Joseph S.
Publicado em 2006

Evaluation of a [(13)C]-Dextromethorphan Breath Test to Assess CYP2D6 Phenotype

Por Leeder, J. Steven, Pearce, Robin E., Gaedigk, Andrea, Modak, Anil, Rosen, David I.
Publicado no J Clin Pharmacol (2008)

Common CYP2D6 polymorphisms affecting alternative splicing and transcription: long-range haplotypes with two regulatory variants modulate CYP2D6 activity

Por Wang, Danxin, Poi, Ming J., Sun, Xiaochun, Gaedigk, Andrea, Leeder, J. Steven, Sadee, Wolfgang
Publicado em 2014

Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children

Por Dinh, Jean C., Pearce, Robin E., Van Haandel, Leon, Gaedigk, Andrea, Leeder, J. Steven
Publicado no Drug Metab Dispos (2016)

Defining Risk Factors for Red Man Syndrome in Children and Adults

Por Myers, Angela L., Gaedigk, Andrea, Dai, Hongying, James, Laura P., Jones, Bridgette L., Neville, Kathleen A.
Publicado em 2012

Long-read single-molecule real-time (SMRT) full gene sequencing of cytochrome P450-2D6 (CYP2D6)

Por Qiao, Wanqiong, Yang, Yao, Sebra, Robert, Mendiratta, Geetu, Gaedigk, Andrea, Desnick, Robert J., Scott, Stuart A.
Publicado no Hum Mutat (2015)

Single Dose, CYP2D6 Genotype-Stratified Pharmacokinetic Study of Atomoxetine in Children with ADHD

Por Brown, Jacob T., Abdel-Rahman, Susan M., van Haandel, Leon, Gaedigk, Andrea, Lin, Yvonne S., Leeder, J. Steven
Publicado no Clin Pharmacol Ther (2016)

CYP2D7 Sequence Variation Interferes with TaqMan CYP2D6(*)15 and (*)35 Genotyping

Por Riffel, Amanda K., Dehghani, Mehdi, Hartshorne, Toinette, Floyd, Kristen C., Leeder, J. Steven, Rosenblatt, Kevin P., Gaedigk, Andrea
Publicado no Front Pharmacol (2016)

Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation

Por Pearce, Robin E., Gaedigk, Roger, Twist, Greyson P., Dai, Hongying, Riffel, Amanda K., Leeder, J. Steven, Gaedigk, Andrea
Publicado no Drug Metab Dispos (2016)

Safety of codeine during breastfeeding: Fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine

Por Madadi, Parvaz, Koren, Gideon, Cairns, James, Chitayat, David, Gaedigk, Andrea, Leeder, J. Steven, Teitelbaum, Ronni, Karaskov, Tatyana, Aleksa, Katarina
Publicado em 2007

In Silico and In Vitro Identification of MicroRNAs That Regulate Hepatic Nuclear Factor 4α Expression

Por Ramamoorthy, Anuradha, Li, Lang, Gaedigk, Andrea, Bradford, L. DiAnne, Benson, Eric A., Flockhart, David A., Skaar, Todd C.
Publicado em 2012

Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infant...

Por Boberg, Mikael, Vrana, Marc, Mehrotra, Aanchal, Pearce, Robin E., Gaedigk, Andrea, Bhatt, Deepak Kumar, Leeder, J. Steven, Prasad, Bhagwat
Publicado no Drug Metab Dispos (2017)

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

Por Gaedigk, Andrea, Jaime, Lazara Karelia Montane, Bertino, Joseph S., Bérard, Anick, Pratt, Victoria M., Bradfordand, L. DiAnne, Leeder, J. Steven
Publicado em 2010

Age-related changes in microRNA expression and pharmacogenes in human liver

Por Burgess, Kimberly S., Philips, Santosh, Benson, Eric A., Desta, Zeruesenay, Gaedigk, Andrea, Gaedigk, Roger, Segar, Matthew W., Liu, Yunlong, Skaar, Todd C.
Publicado no Clin Pharmacol Ther (2015)