Age-related changes in microRNA expression and pharmacogenes in human liver

Developmental changes in the liver can significantly impact drug disposition. Due to the emergence of microRNAs (miRNAs) as important regulators of drug disposition gene expression, we studied age-dependent changes in miRNA expression. Expression of 533 miRNAs was measured in 90 human liver tissues...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Burgess, Kimberly S., Philips, Santosh, Benson, Eric A., Desta, Zeruesenay, Gaedigk, Andrea, Gaedigk, Roger, Segar, Matthew W., Liu, Yunlong, Skaar, Todd C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512918/
https://ncbi.nlm.nih.gov/pubmed/25968989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.145
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