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Age-related changes in microRNA expression and pharmacogenes in human liver

Developmental changes in the liver can significantly impact drug disposition. Due to the emergence of microRNAs (miRNAs) as important regulators of drug disposition gene expression, we studied age-dependent changes in miRNA expression. Expression of 533 miRNAs was measured in 90 human liver tissues...

Полное описание

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Библиографические подробности
Опубликовано в: :Clin Pharmacol Ther
Главные авторы: Burgess, Kimberly S., Philips, Santosh, Benson, Eric A., Desta, Zeruesenay, Gaedigk, Andrea, Gaedigk, Roger, Segar, Matthew W., Liu, Yunlong, Skaar, Todd C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512918/
https://ncbi.nlm.nih.gov/pubmed/25968989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.145
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