Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

Membrane drug transporters contribute to the disposition of many drugs. In human liver, drug transport is controlled by two main superfamilies of transporters, the solute carrier transporters (SLC) and the ATP Binding Cassette transporters (ABC). Altered expression of these transporters due to drug-...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Benson, Eric A., Eadon, Michael T., Desta, Zeruesenay, Liu, Yunlong, Lin, Hai, Burgess, Kimberly S., Segar, Matthew W., Gaedigk, Andrea, Skaar, Todd C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845040/
https://ncbi.nlm.nih.gov/pubmed/27199754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00111
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