Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes

Membrane drug transporters contribute to the disposition of many drugs. In human liver, drug transport is controlled by two main superfamilies of transporters, the solute carrier transporters (SLC) and the ATP Binding Cassette transporters (ABC). Altered expression of these transporters due to drug-...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Benson, Eric A., Eadon, Michael T., Desta, Zeruesenay, Liu, Yunlong, Lin, Hai, Burgess, Kimberly S., Segar, Matthew W., Gaedigk, Andrea, Skaar, Todd C.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845040/
https://ncbi.nlm.nih.gov/pubmed/27199754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00111
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