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Rifampin modulation of xeno‐ and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

Rifampin is a pleiotropic inducer of multiple drug metabolizing enzymes and transporters. This work utilized a global approach to evaluate rifampin effects on conjugating enzyme gene expression with relevance to human xeno‐ and endo‐biotic metabolism. Primary human hepatocytes from 7 subjects were t...

詳細記述

保存先:
書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: Gufford, Brandon T., Robarge, Jason D., Eadon, Michael T., Gao, Hongyu, Lin, Hai, Liu, Yunlong, Desta, Zeruesenay, Skaar, Todd C.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869567/
https://ncbi.nlm.nih.gov/pubmed/29610665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.386
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