Identification of rifampin-regulated functional modules and related microRNAs in human hepatocytes based on the protein interaction network

BACKGROUND: In combination with gene expression profiles, the protein interaction network (PIN) constructs a dynamic network that includes multiple functional modules. Previous studies have demonstrated that rifampin can influence drug metabolism by regulating drug-metabolizing enzymes, transporters...

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Vydáno v:BMC Genomics
Hlavní autoři: Li, Jin, Wang, Ying, Wang, Lei, Dai, Xuefeng, Cong, Wang, Feng, Weixing, Xu, Chengzhen, Deng, Yulin, Wang, Yue, Skaar, Todd C., Liang, Hong, Liu, Yunlong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001204/
https://ncbi.nlm.nih.gov/pubmed/27557147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2909-6
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