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Evaluation of a [(13)C]-Dextromethorphan Breath Test to Assess CYP2D6 Phenotype
A [(13)C]-dextromethorphan ([(13)C]-DM) breath test was evaluated to assess its feasibility as a rapid, phenotyping assay for CYP2D6 activity. [(13)C]-DM (0.5 mg/kg) was administered orally with water or potassium bicarbonate-sodium bicarbonate to 30 adult Caucasian volunteers (n = 1 each): CYP2D6 p...
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| Publicado no: | J Clin Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4791047/ https://ncbi.nlm.nih.gov/pubmed/18728242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0091270008319709 |
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