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Is (+)-[(13)C]-Pantoprazole Better than (±)-[(13)C]-Pantoprazole for the Breath Test to Evaluate CYP2C19 Enzyme Activity?
OBJECTIVE: Recently, we have shown that the (+)-[13C]-pantoprazole is more dependent on CYP2C19 metabolic status than (−)-[13C]-pantoprazole. In this study, we tested the hypothesis that (+)-[(13)C]-pantoprazole is a more sensitive and selective probe for evaluating CYP2C19 enzyme activity than the...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587180/ https://ncbi.nlm.nih.gov/pubmed/23257668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1752-7155/7/1/016001 |
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