In Silico and In Vitro Identification of MicroRNAs That Regulate Hepatic Nuclear Factor 4α Expression

Hepatic nuclear factor 4α (HNF4A) is a nuclear transcription factor that regulates the expression of many genes involved in drug disposition. To identify additional molecular mechanisms that regulate HNF4A, we identified microRNAs (miRNAs) that target HNF4A expression. In silico analyses suggested t...

Full description

Saved in:
Bibliographic Details
Main Authors: Ramamoorthy, Anuradha, Li, Lang, Gaedigk, Andrea, Bradford, L. DiAnne, Benson, Eric A., Flockhart, David A., Skaar, Todd C.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2012
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310421/
https://ncbi.nlm.nih.gov/pubmed/22232426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.040329
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items